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dnmt3ab

Official Full Name
DNA (cytosine-5-)-methyltransferase 3 alpha b
Organism
Danio rerio
GeneID
553189
Background
Predicted to enable DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates; DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates; and metal ion binding activity. Acts upstream of or within regulation of ATP citrate synthase activity; response to temperature stimulus; and swimming behavior. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including auditory capsule; digestive system; eye; pleuroperitoneal region; and spinal cord neural tube. Human ortholog(s) of this gene implicated in Tatton-Brown-Rahman syndrome; hematologic cancer (multiple); and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
dnmt6; dnmt3a1;

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