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Cftr Knockout Mouse Bone Marrow Leukocytes

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Cat.No.
CSC-RK0163
Background
Cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that in humans is encoded by the CFTR gene. CFTR is a ABC transporter-class ion channel that transports chloride and thiocyanate ions across epithelial cell membranes. Mutations of the CFTR gene affect functioning of the chloride ion channels in these cell membranes, leading to cystic fibrosis and congenital absence of the vas deferens.
Growth Properties
Suspension
Host Cell
Bone marrow leukocytes
Ship
Dry ice
Gene Information
Official Symbol
Cftr
Synonyms
CFTR; cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator; cAMP-dependent chloride channel; channel conductance-controlling ATPase; ATP-binding cassette sub-family C member 7; ATP-binding cassette, subfamily c, member 7; ATP-binding cassette transporter sub-family C member 7; Abcc7; AW495489;
Gene ID
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
Function
ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; hydrolase activity; ion channel activity; nucleoside-triphosphatase activity; nucleotide binding;

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