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shRNA set against Mouse CFTR (NM_021050.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH262533

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Gene Information

Cat. No. SHH262533
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CFTR
Gene Name Cftr cystic fibrosis transmembrane conductance regulator [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Cftr cystic fibrosis transmembrane conductance regulator [ Mus musculus ]
Gene Symbol CFTR
Synonyms Abcc7; AW495489
GeneID 12638
Uni ProtID P26361
mRNA Refseq NM_021050.2
Protein Refseq NP_066388.1
Chromosome Location 6 A3; 6 3.1 cM
Function ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; hydrolase activity; ion channel activity; nucleoside-triphosphatase activity; nucleotide binding;
Pathway ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; Pancreatic secretion, organism-specific biosystem; Pancreatic secretion, conserved biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
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