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Panoply™ Human CFTR Knockdown Stable Cell Line

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Cat.No.
CSC-DC003043
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
CFTR
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
CFTR
Synonyms
CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P13569
Chromosome Location
7q31.2
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
Function
ATP binding; ATP-binding and phosphorylation-dependent chloride channel activity; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; protein binding;

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