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Panoply™ Human CFTR Knockdown Stable Cell Line

Cat.No.
CSC-DC003043
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CFTR
Synonyms
CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1
Gene Description
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Gene ID
UniProt ID
P13569
mRNA Refseq
Protein Refseq
Chromosome Location
7q31.2
Function
ATP binding; ATP-binding and phosphorylation-dependent chloride channel activity; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; protein binding;
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
MIM

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