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Human PAX3 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0279
Description
The PAX3 mRNA encodes the human paired box 3 (PAX3) protein, a member of the paired box (PAX) family. PAX3 may regulate cell proliferation, migration and apoptosis and involve in neural development and myogenesis.
Alias
CDHS, HUP2, WS1, WS3
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MTTLAGAVPR MMRPGPGQNY PRSGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPKQVT TPDVEKKIEE YKRENPGMFS WEIRDKLLKD AVCDRNTVPS VSSISRILRS KFGKGEEEEA DLERKEAEES EKKAKHSIDG ILSERASAPQ SDEGSDIDSE PDLPLKRKQR RSRTTFTAEQ LEELERAFER THYPDIYTRE ELAQRAKLTE ARVQVWFSNR RARWRKQAGA NQLMAFNHLI PGGFPPTAMP TLPTYQLSET SYQPTSIPQA VSDPSSTVHR PQPLPPSTVH QSTIPSNPDS SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVMGLLTNHG GVPHQPQTDY ALSPLTGGLE PTTTVSASCS QRLDHMKSLD SLPTSQSYCP PTYSTTGYSM DPVTGYQYGQ YGQSKPWTF
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

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Customer Q&As
What is the molecular weight of Human PAX3 mRNA?

A: The molecular weight of Human PAX3 mRNA is approximately 15000 Daltons.

What is the genomic location of Human PAX3 mRNA?

A: The PAX3 gene is located in the 3p14.1-p12 region of human chromosomes.

What is the cellular localization of Human PAX3 mRNA?

A: The PAX3 gene is widely expressed during embryonic development, especially in the neural tubes, eyes, heart, and muscles.

What is the transcript length of Human PAX3 mRNA?

A: The PAX3 gene has multiple transcripts, ranging in length from 0.9kb to 4.4kb.

What is the role of Human PAX3 mRNA in diseases?

A: The PAX3 gene plays an important role in various diseases, including Waardenburg syndrome, congenital megacolon, and neural tube defects. The occurrence of these diseases is related to mutations and abnormal expression of the PAX3 gene.

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