Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : PMRN-0112
| Cat. No. | PMRN-0112 |
| Description | The IGF1R mRNA encodes the human insulin like growth factor 1 receptor (IGF1R) protein. IGF1R plays a critical role in transformation events. |
| Gene Type | Other |
| RNA Type | mRNA |
| Gene Name | IGF1R |
| Species | Homo sapiens (Human) |
| Alias | CD221, IGFIR, IGFR, JTK13 |
| Features |
• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase |
| Sequence | MKSGSGGGSP TSLWGLLFLS AALSLWPTSG EICGPGIDIR NDYQQLKRLE NCTVIEGYLH ILLISKAEDY RSYRFPKLTV ITEYLLLFRV AGLESLGDLF PNLTVIRGWK LFYNYALVIF EMTNLKDIGL YNLRNITRGA IRIEKNADLC YLSTVDWSLI LDAVSNNYIV GNKPPKECGD LCPGTMEEKP MCEKTTINNE YNYRCWTTNR CQKMCPSTCG KRACTENNEC CHPECLGSCS APDNDTACVA CRHYYYAGVC VPACPPNTYR FEGWRCVDRD FCANILSAES SDSEGFVIHD GECMQECPSG FIRNGSQSMY CIPCEGPCPK VCEEEKKTKT IDSVTSAQML QGCTIFKGNL LINIRRGNNI ASELENFMGL IEVVTGYVKI RHSHALVSLS FLKNLRLILG EEQLEGNYSF YVLDNQNLQQ LWDWDHRNLT IKAGKMYFAF NPKLCVSEIY RMEEVTGTKG RQSKGDINTR NNGERASCES DVLHFTSTTT SKNRIIITWH RYRPPDYRDL ISFTVYYKEA PFKNVTEYDG QDACGSNSWN MVDVDLPPNK DVEPGILLHG LKPWTQYAVY VKAVTLTMVE NDHIRGAKSE ILYIRTNASV PSIPLDVLSA SNSSSQLIVK WNPPSLPNGN LSYYIVRWQR QPQDGYLYRH NYCSKDKIPI RKYADGTIDI EEVTENPKTE VCGGEKGPCC ACPKTEAEKQ AEKEEAEYRK VFENFLHNSI FVPRPERKRR DVMQVANTTM SSRSRNTTAA DTYNITDPEE LETEYPFFES RVDNKERTVI SNLRPFTLYR IDIHSCNHEA EKLGCSASNF VFARTMPAEG ADDIPGPVTW EPRPENSIFL KWPEPENPNG LILMYEIKYG SQVEDQRECV SRQEYRKYGG AKLNRLNPGN YTARIQATSL SGNGSWTDPV FFYVQAKTGY ENFIHLIIAL PVAVLLIVGG LVIMLYVFHR KRNNSRLGNG VLYASVNPEY FSAADVYVPD EWEVAREKIT MSRELGQGSF GMVYEGVAKG VVKDEPETRV AIKTVNEAAS MRERIEFLNE ASVMKEFNCH HVVRLLGVVS QGQPTLVIME LMTRGDLKSY LRSLRPEMEN NPVLAPPSLS KMIQMAGEIA DGMAYLNANK FVHRDLAARN CMVAEDFTVK IGDFGMTRDI YETDYYRKGG KGLLPVRWMS PESLKDGVFT TYSDVWSFGV VLWEIATLAE QPYQGLSNEQ VLRFVMEGGL LDKPDNCPDM LFELMRMCWQ YNPKMRPSFL EIISSIKEEM EPGFREVSFY YSEENKLPEP EELDLEPENM ESVPLDPSAS SSSLPLPDRH SGHKAENGPG PGVLVLRASF DERQPYAHMN GGRKNERALP LPQSSTC |
| Storage | Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers. |
A: Human IGF1R mRNA refers to the Messenger RNA (mRNA) molecule of the Insulin-like growth factor 1 receptor (IGF1R) in the human body.
A: The function of IGF1R mRNA is to code IGF1R protein, which is a Receptor tyrosine kinase and participates in the regulation of cell growth, differentiation and survival.
A: IGF1R mRNA is widely expressed in various tissues of the human body, including the liver, kidneys, lungs, heart, muscles, etc.
A: The expression of IGF1R mRNA is regulated by various factors, including growth factors, hormones, cellular environment, and gene regulatory factors.
A: Yes, IGF1R mRNA mutations are associated with some diseases, such as certain types of cancer, obesity and diabetes.
A: The expression level of IGF1R mRNA affects cell growth and proliferation, with high expression levels usually associated with enhanced cell growth and proliferation, while low expression levels are the opposite.
A: IGF1R mRNA plays an important role in tumors, as it is involved in regulating the proliferation, metastasis, and drug resistance of tumor cells.
A: The expression of IGF1R mRNA is age related, and the expression level of IGF1R mRNA may change with age.
A: Yes, some studies suggest that mutations in IGF1R mRNA may be associated with drug resistance, which is of great significance for tumor treatment.
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Very simple and fast to obtain IGF1R mRNA, one vial can be used for a long time.
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