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Human SCN8A Stable Cell Line-CHO

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Cat.No.
CSC-RI0168
Background
The human SCN8A gene encodes the pore-forming subunit of Nav1.6, a voltage-gated sodium channel expressed in central and peripheral nervous systems. Mutations in the mouse ortholog cause ataxia and other movement disorders. Nav1.6 channels are therapeutic targets in multiple sclerosis and seizure.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
SCN8A
Synonyms
SCN8A; sodium channel, voltage gated, type VIII, alpha subunit; MED, sodium channel, voltage gated, type VIII, alpha polypeptide; sodium channel protein type 8 subunit alpha; CerIII; NaCh6; Nav1.6; PN4; hNa6/Scn8a voltage-gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.6; MED; CIAT; CERIII; EIEE13; FLJ33996;
Gene ID
MIM
UniProt ID
Q9UQD0
Chromosome Location
12q13.1
Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem;
Function
ATP binding; nucleotide binding; voltage-gated ion channel activity; voltage-gated sodium channel activity; voltage-gated sodium channel activity;

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