Human OPRK1-tGFP Stable Cell Line-U2OS

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Cat.No.

CSC-RG0034

Background

kappa-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. Opioid receptors mediate the analgesic action and addictive properties of opioid drugs. The kappa-opioid receptor may provide a natural addiction control mechanism, and consequently selective agonists of this receptor may have therapeutic potential in the treatment of addiction.

Growth Properties

Adherent

Morphology

Epithelial

Host Cell

U2OS

Ship

Dry ice

Gene Information

Gene Name

OPRK1 opioid receptor, kappa 1 [ Homo sapiens ]

Official Symbol

OPRK1

Synonyms

OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR; KOR-1; K-OR-1; kappa opioid receptor; Opiate receptor, kappa-1; OPRK;

Gene ID

4986

MIM

165196

UniProt ID

P41145

Chromosome Location

8q11.2

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;

Function

G-protein coupled receptor activity; dynorphin receptor activity; protein binding; receptor activity; signal transducer activity;

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