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Rat Oprk1 Stable Cell Line-CHO dhfr-

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Cat.No.
CSC-RG0341
Background
Kappa opioid receptor (KOR) is a receptor for dynorphins. KOR inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance and may play a role in arousal and regulation of autonomic and neuroendocrine functions. Some studies suggest that the stimulation of kappa opioid receptors improves memory dysfunctions resulting from the blockade of muscarinic M1 receptors. In addition, there is evidence that kappa opioid receptor agonists attenuate several behavioral responses induced by drugs of abuse, raising the possibility that kappa opioid receptor agonists may be useful for the treatment of dependence on drugs of abuse.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO dhfr-
Ship
Dry ice
Gene Information
Official Symbol
Oprk1
Synonyms
OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR-1; K-OR-1;
Gene ID
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; dynorphin receptor activity; receptor activity; signal transducer activity;
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AD11241Z
>1x 10^9 vp/ml
1 x 0.2 ml
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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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