Rat Oprk1 ORF Clone(NM_017167.2)

Name: Rat Oprk1 ORF Clone(NM_017167.2)
SKU: CDCR378233
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR378233

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Product Information

Gene Information

Cat. No.	CDCR378233
Product Type	ORF Clone
Gene Abbr	Oprk1
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	1143 bp
Vector	pCMV6-Entry

Target Gene

OPRK1

Background

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

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