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Human NTSR1 Stable Cell Line-CHO

Human NTSR1 Stable Cell Line-CHO

Cat.No. :  CSC-RG0902 Host Cell:  CHO-K1

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Cat. No. CSC-RG0902
Gene NTSR1
Gene Species Homo sapiens (Human)
Alias NTSR1, NTR, NTR1, NTRH, NT-R-1
Host Cell CHO-K1
Species Cricetulus griseus (Chinese hamster)
Morphology Epithelial-like
Stability Validated for at least 10 passages
Application

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Shipping Dry ice
Storage Liquid nitrogen
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties Adherent
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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Neurotensin (NT) is a brain and gastrointestinal peptide that fulfills a dual function of neurotransmitter or neuromodulator in the nervous system and of local hormone in the periphery. NT is a neuromodulator of dopamine transmission and of anterior pituitary hormone secretion, and exerts potent hypothermic and analgesic effects in the brain. In the periphery, NT is a paracrine and endocrine modulator of the digestive tract and of the cardiovascular system of mammals and acts as a growth factor on a variety of normal or cancer cells. NT plays many central and peripheral functions through its interaction with specific receptors. Three subtypes of neurotensin receptors, NTSR1, NTSR2 and NTSR3, have been cloned so far. Among them, NTSR1 and NTSR2 belong to the family of G protein-coupled receptors and mediate the most known functions of NT, whereas the third neurotensin receptor's function remains to be established.
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