Panoply™ Human SMG7 Knockdown Stable Cell Line

Name: Panoply™ Human SMG7 Knockdown Stable Cell Line
SKU: CSC-DC014753
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC014753

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC014753
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SMG7
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SMG7 smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) [ Homo sapiens ]
Gene Symbol	SMG7
Synonyms	SMG7; smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans); C1orf16, chromosome 1 open reading frame 16; protein SMG7; EST1 telomerase component homolog C (S. cerevisiae); EST1C; KIAA0250; SGA56M; SMG 7; EST1-like protein C; ever shorter telomeres 1C; EST1 telomerase component homolog C; breast cancer-associated antigen SGA-56M; C1orf16; FLJ23717;
Gene ID	9887
Uni Prot ID	Q92540
m RNA Refseq	BC036381
Chromosome Location	1q25
Function	protein binding; protein phosphatase 2A binding;
Pathway	Gene Expression, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem;
MIM	610964

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