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Panoply™ Human PARN Knockdown Stable Cell Line

Cat.No.
CSC-DC011311
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PARN
Synonyms
PARN; poly(A)-specific ribonuclease; poly(A) specific ribonuclease (deadenylation nuclease); poly(A)-specific ribonuclease PARN; DAN; deadenylation nuclease; deadenylating nuclease; polyadenylate-specific ribonuclease; poly(A)-specific ribonuclease (deadenylation nuclease);
Gene ID
UniProt ID
O95453
mRNA Refseq
BC050029
Chromosome Location
16p13
Function
RNA binding; exonuclease activity; hydrolase activity; mRNA 3-UTR binding; metal ion binding; nuclease activity; nucleotide binding; poly(A)-specific ribonuclease activity; protein kinase binding;
Pathway
Activation of Genes by ATF4, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem;
MIM

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