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Panoply™ Human GRIN2B Knockdown Stable Cell Line

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Cat.No.
CSC-DC006660
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
GRIN2B
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
GRIN2B
Synonyms
MRD6; NR2B; hNR3; GluN2B; NMDAR2B
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q13224
Chromosome Location
12p12
Pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem;
Function
D2 dopamine receptor binding; N-methyl-D-aspartate selective glutamate receptor activity; beta-catenin binding; calcium channel activity; cell adhesion molecule binding; drug binding; extracellular-glutamate-gated ion channel activity; glycine binding; ionotropic glutamate receptor binding; neurotransmitter binding; protein binding; protein heterodimerization activity; zinc ion binding;

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