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Human QRFPR Stable Cell Line-CHO

See other products for QRFPR
Cat.No.
CSC-RG0853
Background
GPR103 is a G-protein coupled receptor that has been shown to be expressed primarily in brain, heart, kidney, adrenal gland, retina and testis. Its ligand has been identified as a 43-residue RF-amide peptide known as QRFP. When administered centrally in mice, QRFP was shown to increase feeding, behavioral arousal and blood pressure. When administered iv, this peptide caused release of aldosterone. Knockout mice (GPR103 -/-) have suggested a role of GPR103 in regulating bone formation. These diverse but important physiological functions of this receptor and ligand make them important possible targets for drug discovery in several fields.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
At least 6 passages
Ship
Dry ice
Gene Information
Official Symbol
QRFPR
Synonyms
QRFPR; pyroglutamylated RFamide peptide receptor; G protein coupled receptor 103 , GPR103; QRFP receptor; G protein-coupled receptor 103; G-protein coupled receptor 103; orexigenic neuropeptide QRFP receptor; AQ27; GPR103; SP9155; MGC149217;
Gene ID
MIM
UniProt ID
Q96P65
Chromosome Location
4q27
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Orexin and neuropeptides FF and QRFP bind to their respective receptors, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
G-protein coupled receptor activity; neuropeptide Y receptor activity; receptor activity; signal transducer activity;
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AD13270Z
>1x 10^9 vp/ml
1 x 0.2 ml
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Fax: 1-631-614-7828
Email: info@creative-biogene.com

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Email: info@creative-biogene.com
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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