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Human FFAR3 Stable Cell Line-CHO

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Cat.No.
CSC-RG0059
Background
Free fatty acid receptor 3 (FFA3) is a G-protein coupled receptor that in humans is encoded by the FFAR3 gene. Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate >acetate >formate.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
FFAR3
Synonyms
FFAR3; free fatty acid receptor 3; G protein coupled receptor 41 , GPR41; FFA3R; G protein-coupled receptor 41; G-protein coupled receptor 41; GPR41;
Gene ID
MIM
UniProt ID
O14843
Chromosome Location
19q13.1
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Free fatty acid receptors, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity;

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