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Zfp423

Official Full Name
zinc finger protein 423
Organism
Mus musculus
GeneID
94187
Background
Enables sequence-specific DNA binding activity. Involved in several processes, including brown fat cell differentiation; negative regulation of cold-induced thermogenesis; and positive regulation of BMP signaling pathway. Acts upstream of or within several processes, including cerebellar granule cell precursor proliferation; protein localization to cilium; and smoothened signaling pathway. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; genitourinary system; and sensory organ. Used to study Dandy-Walker syndrome and cerebellar disease. Human ortholog(s) of this gene implicated in nephronophthisis 14. Orthologous to human ZNF423 (zinc finger protein 423). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Zfp423; Roaz; Ebfaz; nur12; Zfp104; Znf423; ataxia1; mKIAA0760;

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