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Tubb5

Official Full Name
tubulin, beta 5 class I
Organism
Mus musculus
GeneID
22154
Background
A structural constituent of cytoskeleton. Involved in regulation of synapse organization. Acts upstream of or within spindle assembly. Located in microtubule and nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and retina. Used to study microcephaly. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Tubb5; M(beta)5; B130022C14Rik;

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