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TMC8


Official Full Name
transmembrane channel like 8
Organism
Homo sapiens
Gene ID
147138
Background
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008]
Synonyms
EV2; EVER2; EVIN2

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SHH428416 shRNA set against Human TMC8 (NM_152468.4) Inquiry
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CDCR243381 Mouse Tmc8 ORF Clone(NM_001195089.1) Inquiry
CDCR243383 Mouse Tmc8 ORF Clone(NM_001195090.1) Inquiry
CDCR275692 Mouse Tmc8 ORF Clone(NM_181856.2) Inquiry
CDCR319554 Human TMC8 ORF Clone(NM_152468.4) Inquiry
CDCS417160 Human TMC8 ORF Clone (BC141865) Inquiry
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