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Siah1B

Official Full Name
siah E3 ubiquitin protein ligase 1B
Organism
Mus musculus
GeneID
20438
Background
This gene encodes a member of the seven in absentia homolog (Siah) family of E3 ubiquitin ligase enzymes that catalyze the transfer of ubiquitin to substrate proteins. The encoded protein targets Pard3A (partitioning defective 3A) protein for proteasome-mediated degradation during the exit of cerebellar granule neurons from their germinal zone niche. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Synonyms
Siah1b; Sinh1b; siah-1b;

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