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sox11a

Official Full Name
SRY-box transcription factor 11a
Organism
Danio rerio
GeneID
30602
Background
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development; camera-type eye development; and negative regulation of smoothened signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including mesoderm; nervous system; neural keel; pleuroperitoneal region; and somite. Used to study Coffin-Siris syndrome. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 9. Orthologous to human SOX11 (SRY-box transcription factor 11). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
cb237; id:ibd2104; wu:fb16g02; zgc:136533;

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