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raf1b

Official Full Name
Raf-1 proto-oncogene, serine/threonine kinase b
Organism
Danio rerio
GeneID
557109
Background
Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in MAPK cascade. Predicted to act upstream of or within protein phosphorylation and signal transduction. Predicted to be located in plasma membrane. Predicted to be active in cytosol and mitochondrion. Is expressed in brain. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Feb 2025]

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