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ptena

Official Full Name
phosphatase and tensin homolog A
Organism
Danio rerio
GeneID
794088
Background
Enables lipid phosphatase activity. Acts upstream of or within several processes, including hepatocyte proliferation; lifelong otolith mineralization; and phosphatidylinositol dephosphorylation. Predicted to be located in several cellular components, including PML body; dendritic spine; and postsynaptic density. Predicted to be active in several cellular components, including cytosol; nucleus; and plasma membrane. Is expressed in several structures, including nervous system; oocyte; otic vesicle; presumptive neural retina; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including PTEN hamartoma tumor syndrome (multiple); breast cancer (multiple); liver disease (multiple); nervous system cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human PTEN (phosphatase and tensin homolog). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
zgc:73086; wu:fc52g04;

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