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PNLIP

Official Full Name
pancreatic lipase
Background
Pancreatic lipase, also known as pancreatic triacylglycerol lipase, is secreted from the pancreas, and is the primary lipase (enzyme) that hydrolyzes (breaks down) dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Triacylglycerol + H2O diacylglycerol + a fatty acid anion Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal. This protein belongs to pancreatic lipase family.
Synonyms
PNLIP; pancreatic lipase; PL; PTL; pancreatic triacylglycerol lipase; OTTHUMP00000020564; triacylglycerol acylhydrolase; Lipase; PNLIPD; PNLIPRP2

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