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Ndel1

Official Full Name
nudE neurodevelopment protein 1-like 1
Background
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
NDEL1; nudE nuclear distribution E homolog (A. nidulans)-like 1; nudE nuclear distribution gene E homolog (A. nidulans) like 1; nuclear distribution protein nudE-like 1; MITAP1; NUDEL; protein Nudel; endooligopeptidase A; mitosin-associated protein 1; mit; mitosin-associated protein MITAP1; nudE nuclear distribution gene E homolog-like 1; EOPA; DKFZp451M0318; EOPA, NUDEL, MITAP1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution gene E homolog like 1

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