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Naip2

Official Full Name
NLR family, apoptosis inhibitory protein 2
Organism
Mus musculus
GeneID
17948
Background
Predicted to enable ATP binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein serine/threonine kinase binding activity. Involved in defense response to bacterium; detection of bacterium; and pyroptotic inflammatory response. Acts upstream of or within cellular response to estrogen stimulus. Part of IPAF inflammasome complex. Is expressed in several structures, including central nervous system; heart; liver; male reproductive system; and urinary system. Orthologous to human NAIP (NLR family apoptosis inhibitory protein). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Naip2; Birc1b; Naip-rs6;

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