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MED25

Official Full Name
mediator complex subunit 25
Organism
Homo sapiens
GeneID
81857
Background
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]
Synonyms
P78; ACID1; ARC92; BVSYS; PTOV2; CMT2B2; TCBAP0758;

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