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kitb

Official Full Name
KIT proto-oncogene, receptor tyrosine kinase b
Organism
Danio rerio
GeneID
497629
Background
Predicted to enable growth factor binding activity and transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within embryonic hemopoiesis. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including gonad; immune system; nervous system; otic vesicle; and ventral mesoderm. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal stromal tumor; germ cell cancer (multiple); mastocytosis; piebaldism; and renal cell carcinoma. Orthologous to human KIT (KIT proto-oncogene, receptor tyrosine kinase). [provided by Alliance of Genome Resources, Feb 2025]

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