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ITGB2

Official Full Name
integrin subunit beta 2
Organism
Homo sapiens
GeneID
3689
Background
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1;

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