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igf1ra

Official Full Name
insulin-like growth factor 1a receptor
Organism
Danio rerio
GeneID
245701
Background
Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process and insulin-like growth factor binding activity. Acts upstream of or within several processes, including embryonic organ development; fin regeneration; and insulin-like growth factor receptor signaling pathway. Predicted to be located in membrane. Predicted to be part of insulin receptor complex. Predicted to be active in axon and plasma membrane. Is expressed in several structures, including digestive system; female organism; male organism; musculature system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; dementia (multiple); kidney cancer (multiple); liver disease (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
IGF-IRa; sb:eu1090; wu:fi20b10;

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