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Hbb-Bh1

Official Full Name
hemoglobin Z, beta-like embryonic chain
Organism
Mus musculus
GeneID
15132
Background
Predicted to enable several functions, including heme binding activity; hemoglobin alpha binding activity; and oxygen binding activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in several structures, including aorta-gonad-mesonephros; extraembryonic component; genitourinary system; hemolymphoid system; and tail bud. Human ortholog(s) of this gene implicated in delta beta-thalassemia and sickle cell anemia. Orthologous to human HBE1 (hemoglobin subunit epsilon 1); HBG1 (hemoglobin subunit gamma 1); and HBG2 (hemoglobin subunit gamma 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Hbb-bh1; betaH1;

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