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H2-M3

Official Full Name
histocompatibility 2, M region locus 3
Organism
Mus musculus
GeneID
14991
Background
Enables peptide antigen binding activity. Acts upstream of or within several processes, including positive regulation of biosynthetic process; positive regulation of leukocyte mediated cytotoxicity; and response to bacterium. Located in external side of plasma membrane. Part of MHC class Ib protein complex. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in asthma and hepatitis C. Orthologous to human HLA-G (major histocompatibility complex, class I, G). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
H2-M3; Hmt; M3a; R4B2; H-2M3; MuprM3; MuprM301; MuprM302;

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