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Gm4788

Official Full Name
complement factor H-related 4
Organism
Mus musculus
GeneID
214403
Background
Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in complement activation; proteolysis; and regulation of complement activation, alternative pathway. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; lupus nephritis; and systemic lupus erythematosus. Orthologous to human CFH (complement factor H). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Cfhrc; Gm4788; EG214403;

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