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GLUL

Official Full Name
glutamate-ammonia ligase
Background
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
Synonyms
GLUL; glutamate-ammonia ligase; GS; GLNS; PIG43; PIG59; glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59; GLNS, glutamate ammonia ligase (glutamine synthase); GLNS, GS, PIG43, PIG59, GLUL; p42; glutamate-ammonia ligase (glutamine synthase); glutamate-ammonia ligase (glutamine synthetase)

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