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bmpr2b

Official Full Name
bone morphogenetic protein receptor, type II b (serine/threonine kinase)
Organism
Danio rerio
GeneID
555655
Background
Enables transforming growth factor beta receptor activity. Acts upstream of or within several processes, including BMP signaling pathway; circulatory system development; and fin regeneration. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including blood island; cardiovascular system; gonad; gut; and posterior pronephric duct. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease 1. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2). [provided by Alliance of Genome Resources, Feb 2025]

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