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BCAR3


Official Full Name
BCAR3 adaptor protein, NSP family member
Organism
Homo sapiens
Gene ID
8412
Background
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Synonyms
MIG7; NSP2; AND-34; SH2D3B

Cat.No. Product Name Price
SHH245698 shRNA set against Mouse BCAR3 (NM_013867.2) Inquiry
SHH245694 shRNA set against Human BCAR3 (NM_003567.3) Inquiry
SHH245702 shRNA set against Rat BCAR3 (NM_001107722.1) Inquiry
SHW012233 shRNA set against Danio rerio BCAR3 (NM_001113620) Inquiry
Cat.No. Product Name Price
CDFR007366 Rat Bcar3 cDNA Clone(NM_001107722.1) Inquiry
MiUTR3H-07024 BCAR3 miRNA 3'UTR clone Inquiry
CDCB173708 Danio rerio BCAR3 ORF Clone (NM_001113620) Inquiry
CDCB186427 Rabbit BCAR3 ORF clone (XM_008264864.1) Inquiry
CDCG011083 Mouse BCAR3 ORF clone(NM_013867.2) Inquiry
CDCR374441 Rat Bcar3 ORF Clone(NM_001107722.1) Inquiry
CDCS411358 Human BCAR3 ORF Clone (BC039895) Inquiry
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