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Aes

Official Full Name
amino-terminal enhancer of split
Background
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
AES; amino-terminal enhancer of split; GRG; ESP1; GRG5; TLE5; AES-1; AES-2; gp130-associated protein GAM; zgc:64216;

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