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AURKC

Official Full Name
aurora kinase C
Organism
Homo sapiens
GeneID
6795
Background
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Synonyms
AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C;

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