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ANAPC11

Official Full Name
APC11 anaphase promoting complex subunit 11 homolog (yeast)
Background
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Synonyms
ANAPC11; anaphase promoting complex subunit 11; APC11; Apc11p; MGC882; HSPC214; Anaphase-promoting complex subunit 11; Cyclosome subunit 11; Hepatocellular carcinoma-associated RING finger protein; APC11 anaphase promoting complex subunit 11 homolog; anaphase promoting complex subunit 11 (yeast APC11 homolog); APC11 anaphase promoting complex subunit 11 homolog (yeast); zgc:153671; si:dkey-237i9.4

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