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As one of the leading biotechnology company in the world, Creative Biogene has the ability to develop and optimize custom probiotics to meet your pharmaceutical applications. Creative Biogene’s sophisticated equipments, mature technology platform and highly experienced staffs are able to help you carry out your specific project as cost effectively, quickly and simply as possible, without compromising on quality. Besides, with the help of professional scientist, Creative Biogene can provide you with the most affordable service to ensure your satisfaction in a timely and professional manner.

Probiotics are defined as “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. In the case of probiotics, the main health benefits appear to be associated with maintenance of healthy microbiota, by reducing the numbers or colonization of pathogenic bacteria or viruses and by maintaining and improving the intestinal barrier function. Specific probiotics may also be associated with other health benefits including desirable modulation of lactose intolerance, bowel function and gastrointestinal comfort, diarrhea prevention and symptom alleviation, and upregulation or downregulation of immune response.


Although probiotics may have benefits described above, it is a well-established fact that the biological effects of probiotics are strain specific. Stig Bengmark has made this very clear in his statement that the genetic difference between one probiotic and the other is larger than the difference between a man and a goldfish. The success (or failure) of one strain cannot be extrapolated to another strain (or strains). The strain-specific benefits of probiotics emphasize the need for proper strain discovery, identification and modification. Creative Biogene as a leading biotechnology service vendor in the world can help customers worldwide to construct modified microorganisms which can be used as probiotics to meet your pharmaceutical needs.

As a leading biotechnology company, Creative Biogene has years of professional and abundant experience which can provide you with the most affordable and high-quality microbe genome editing service to satisfy your downstream needs. Creative Biogene has confidence in speeding your microbe genome editing project and delivering the final products with fast turnaround time.


  1. Rijkers GT, et al. Health benefits and health claims of probiotics: bridging science and marketing. British Journal of Nutrition, 2011, 106(09): 1291-1296.
  2. Brown AC, Valiere A. Probiotics and medical nutrition therapy. Nutrition in clinical care: an official publication of Tufts University, 2004, 7(2): 56.
  3. Seppo Salminen, Henk van Loveren. Probiotics and prebiotics: health claim substantiation. Microb Ecol Health Dis. 2012; 23: 10.3402/mehd.v23i0.18568.

For research use only. Not intended for any clinical use.