Human ORF Clones
Proteins are the major functional building blocks that determine the fate of cells, tissues and organisms. Studies of protein function often require high-quality plasmid clones containing the relevant open reading frames (ORFs) in a format compatible with protein expression. High-throughput methods have increasingly created a need for clones encoding a class of proteins of interest or the entire proteome of a species. Utilizing recombinant cloning vectors and containing only the coding sequence, with all non-translated sequences removed, ensures maximum flexibility, including protein expression over a wide range of experiments, and provides various labeling options for either end of the protein.
ORFs are genes that have been identified as key building blocks of proteins. They have great potential to advance biomedical research, genetic engineering and disease treatment, especially when human ORF clones are used in these studies. Understanding the role and potential applications of human ORF cloning is critical for researchers, clinicians, and those in biotechnology. However, for many eukaryotic species, including humans, the number of protein-coding sequences exceeds 15,000 genes, making it daunting and expensive to produce sequence-verified comprehensive collections of ORF clones.
cDNAs are ideal for overexpressing genes in natural regulatory contexts, while ORFs delete the 5' and 3' UTRs, providing a shortcut for protein expression. Creative Biogene offers the largest collection of ORF clones, with genome-wide coverage for humans. All human ORF clones can be easily expressed with various combinations of fusion tags (fluorescence, antibody, solubility, purification or no tag), promoters and selection markers for easy expression in different host systems.
- Expression validated by Western Blot
- Sequence verified
- No need for subcloning
- High purity and low endotoxicity
- The human ORF clones collection contains over 30,000 clones
Creative Biogene can accelerate your research by providing sequence-verified human ORFs. Please browse our human ORF clones collection to find your desired one.
Browse All Human ORF Clones
* For research use only. Not intended for any clinical use.