Recombinant Human EGFR (C-6His)

Name: Recombinant Human EGFR (C-6His)
SKU: RP00041

Cat.No. : RP00041 Tag: C-6His

Expressed Region: Leu25-Ser645 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00041
Description	The Recombinant Human EGFR (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu25-Ser645 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	69.6 KDa
Expressed Region	Leu25-Ser645
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 50mM Nacl, 0.05% Tween80, pH8.0.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	EGFR
Background	The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Synonyms	Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR;ERBB; ERBB1; HER1

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