Recombinant Mouse TSLP (C-Fc)

Name: Recombinant Mouse TSLP (C-Fc)
SKU: RP00003

Cat.No. : RP00003 Tag: C-Fc

Expressed Region: Tyr20-Glu140 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00003
Description	The Recombinant Mouse TSLP (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Tyr20-Glu140 with a Fc tag at the C terminus.
Species	Mouse
Tag	C-Fc
Mol. Weight	41.1 KDa
Expressed Region	Tyr20-Glu140
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Tslp
Background	This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.
Synonyms	Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp

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