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Hendra virus (HeV) is a member of the genus Henipavirus in the family Paramyxoviridae. HeV is a bat-borne virus associated with highly lethal infections in horses and humans. Many disease outbreaks in Australian horses are caused by Hendra virus. Symptoms of Hendra virus infection in humans may be respiratory symptoms, including hemorrhage and edema of the lungs, or in some cases viral meningitis. In horses, infection typically causes one or more pulmonary edema, congestion, and neurological signs.
The HeV genome structure is similar to viruses found in the genera Respirovirus and Morbillivirus. A striking molecular feature of Henipavirus is its large genome compared with other paramyxoviruses: HeV has 18,234 nucleotides. The genomic RNA of henipavirus is encapsidated by a nucleoprotein (N), a phosphoprotein (P), and an RNA-dependent RNA polymerase (large protein; L), which is also a minority protein of the nucleocapsid.
In the context of molecular biology, an open reading frame (ORF) refers to a sequence in the genome that has the potential to be translated into a protein. Characterization and cloning of these sequences are fundamental to pathogen research, vaccine development, and drug design, making ORF cloning an indispensable tool in the study of viral pathology. Through the HeV ORF clone, researchers aim to gain insights into HeV—from its pathogenesis to developing effective control measures.
Combining unique and versatile cloning technologies, Creative Biogene has created a large number of high-quality HeV ORF clones. Premade ORF clones eliminate the initial cloning and validation procedures for gene discovery studies. There is no need to perform tedious RNA isolation, cDNA synthesis, cloning, sequencing, and validation procedures steps.
Please browse our collection of HeV ORF clones to find the one you want.
| Cat.No. | Product Name | Price |
|---|---|---|
| CDCB156831 | HeV HeV-G ORF clone (AF017149.3) | Inquiry |
| CDCB156832 | HeV HeV-F ORF clone (AF017149.3) | Inquiry |
| CDCB156833 | HeV HeV-M ORF clone (AF017149.3) | Inquiry |
| CDCB156834 | HeV HeV-N ORF clone (AF017149.3) | Inquiry |
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