Recombinant Rhesus Macaque LILRB1 (C-Fc)

Name: Recombinant Rhesus Macaque LILRB1 (C-Fc)
SKU: RP00115
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00115 Tag : C-Fc

Expressed Region : Ser17-His456 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00115
Description	The Recombinant Rhesus Macaque LILRB1 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Ser17-His456 with a Fc tag at the C terminus.
Species	Rhesus Macaque
Tag	C-Fc
Mol Weight	74.6 KDa
Format	Powder
Expressed Region	Ser17-His456
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	LILRB1
Synonyms	LILRB1; CD85j; ILT2

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Background

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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

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