Recombinant Human TREM2 (C-Fc)

Name: Recombinant Human TREM2 (C-Fc)
SKU: RP00168

Cat.No. : RP00168 Tag: C-Fc

Expressed Region: His19-Ser174 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00168
Description	The Recombinant Human TREM2 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is His19-Ser174 with a Fc tag at the C terminus.
Species	Human
Tag	C-Fc
Mol. Weight	44.4 KDa
Expressed Region	His19-Ser174
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	TREM2
Background	This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	Triggering receptor expressed on myeloid cells 2; TREM2; Triggering receptor expressed on monocytes 2; TREM-2

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