Recombinant Human CPB2 (C-6His)

Name: Recombinant Human CPB2 (C-6His)
SKU: RP00134
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00134 Tag : C-6His

Expressed Region : Phe23-Val423 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00134
Description	The Recombinant Human CPB2 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Phe23-Val423 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	47 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Phe23-Val423
Expression System	Human Cell
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM ZnCl₂, 10% Glycerol, pH8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	CPB2
Background	Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.
Synonyms	Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma Carboxypeptidase B; pCPB; Thrombin-Activable Fibrinolysis Inhibitor; TAFI; CPB2

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