midline 1 - Creative Biogene

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MID1

Official Full Name

midline 1

Organism

Homo sapiens

GeneID

4281

Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Synonyms

OS; FXY; OSX; GBBB; OGS1; XPRF; BBBG1; GBBB1; MIDIN; RNF59; ZNFXY; TRIM18;

Cat.No.	Product Name	Price
CLKO-1515	MPG KO Cell Lysate-HeLa	Inquiry
CSC-DC009512	Panoply™ Human MID1 Knockdown Stable Cell Line	Inquiry
CSC-DC009669	Panoply™ Human MPG Knockdown Stable Cell Line	Inquiry
CSC-RK0220	Human MPG Knockdown Cell Line - Glioma	Inquiry
CSC-RT1668	Human MPG Knockout Cell Line-HeLa	Inquiry
CSC-SC009512	Panoply™ Human MID1 Over-expressing Stable Cell Line	Inquiry
CSC-SC009669	Panoply™ Human MPG Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CLKO-1515	MPG KO Cell Lysate-HeLa	Inquiry
CSC-DC009512	Panoply™ Human MID1 Knockdown Stable Cell Line	Inquiry
CSC-DC009669	Panoply™ Human MPG Knockdown Stable Cell Line	Inquiry
CSC-RK0220	Human MPG Knockdown Cell Line - Glioma	Inquiry
CSC-RT1668	Human MPG Knockout Cell Line-HeLa	Inquiry
CSC-SC009512	Panoply™ Human MID1 Over-expressing Stable Cell Line	Inquiry
CSC-SC009669	Panoply™ Human MPG Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CLKO-1515	MPG KO Cell Lysate-HeLa	Inquiry
CSC-DC009512	Panoply™ Human MID1 Knockdown Stable Cell Line	Inquiry
CSC-DC009669	Panoply™ Human MPG Knockdown Stable Cell Line	Inquiry
CSC-RK0220	Human MPG Knockdown Cell Line - Glioma	Inquiry
CSC-RT1668	Human MPG Knockout Cell Line-HeLa	Inquiry
CSC-SC009512	Panoply™ Human MID1 Over-expressing Stable Cell Line	Inquiry
CSC-SC009669	Panoply™ Human MPG Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CLKO-1515	MPG KO Cell Lysate-HeLa	Inquiry
CSC-DC009512	Panoply™ Human MID1 Knockdown Stable Cell Line	Inquiry
CSC-DC009669	Panoply™ Human MPG Knockdown Stable Cell Line	Inquiry
CSC-RK0220	Human MPG Knockdown Cell Line - Glioma	Inquiry
CSC-RT1668	Human MPG Knockout Cell Line-HeLa	Inquiry
CSC-SC009512	Panoply™ Human MID1 Over-expressing Stable Cell Line	Inquiry
CSC-SC009669	Panoply™ Human MPG Over-expressing Stable Cell Line	Inquiry

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