Human MPG Knockdown Cell Line - Glioma

Name: Human MPG Knockdown Cell Line - Glioma
SKU: CSC-RK0220
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0220

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0220
Description	This cell line is engineered to stably express shRNA targeting human MPG.
Target Gene	MPG
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MPG N-methylpurine-DNA glycosylase [ Homo sapiens ]
Gene Symbol	MPG
Synonyms	MPG; N-methylpurine-DNA glycosylase; DNA-3-methyladenine glycosylase; alkyladenine DNA glycosylase; MDG; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; proliferation-inducing protein 11; proliferation-inducing protein 16; N-methylpurine-DNA glycosylase, MPG; CRA36.1 (3-methyl-adenine DNA glycosylase); 3 end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; AAG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1;
Gene ID	4350
Uni Prot ID	P29372
m RNA Refseq	BC014991
Chromosome Location	16p13.3
Function	DNA binding; DNA-3-methyladenine glycosy
Pathway	Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM	156565

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