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IRF5

Official Full Name
interferon regulatory factor 5
Background
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
Synonyms
IRF5; interferon regulatory factor 5; SLEB10; IRF-5; OTTHUMP00000212904; OTTHUMP00000212905; OTTHUMP00000212907; OTTHUMP00000212910; zgc:76986; im:7155364

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